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Calcineurin regulates innate antifungal immunity in neutrophils

Patients taking immunosuppressive drugs, like cyclosporine A (CsA), that inhibit calcineurin are highly susceptible to disseminated fungal infections, although it is unclear how these drugs suppress resistance to these opportunistic pathogens. We show that in a mouse model of disseminated Candida al...

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Main Authors: Greenblatt, Matthew B., Aliprantis, Antonios, Hu, Bella, Glimcher, Laurie H.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867274/
https://ncbi.nlm.nih.gov/pubmed/20421389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092531
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