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MyD88-dependent TLR4 signaling is selectively impaired in alveolar macrophages from asymptomatic HIV(+) persons
Alveolar macrophages (AMs) are the predominant effector cell in the lungs and contribute to a critical first line of defense against bacterial pathogens through recognition by pattern recognition receptors such as Toll-like receptor 4 (TLR4). TLR4-mediated tumor necrosis factor α (TNFα) release is s...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867269/ https://ncbi.nlm.nih.gov/pubmed/20197549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-250787 |
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