Staphylococcus aureus recognition by hematopoietic stem and progenitor cells via TLR2/MyD88/PGE(2) stimulates granulopoiesis in wounds

During bacterial infection, hematopoietic stem and progenitor cells (HSPCs) differentiate into polymorphonuclear leukocytes (PMNs) in the bone marrow. We reported that HSPCs recruited to Staphylococcus aureus–infected skin wounds in mice undergo granulopoiesis, whereas other authors have demonstrate...

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Bibliographic Details
Main Authors: Granick, Jennifer L., Falahee, Patrick C., Dahmubed, Delsheen, Borjesson, Dori L., Miller, Lloyd S., Simon, Scott I.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2013
Subjects:
Phagocytes, Granulocytes, and Myelopoiesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765058/
https://ncbi.nlm.nih.gov/pubmed/23869087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-466268
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