Staphylococcus aureus recognition by hematopoietic stem and progenitor cells via TLR2/MyD88/PGE(2) stimulates granulopoiesis in wounds

During bacterial infection, hematopoietic stem and progenitor cells (HSPCs) differentiate into polymorphonuclear leukocytes (PMNs) in the bone marrow. We reported that HSPCs recruited to Staphylococcus aureus–infected skin wounds in mice undergo granulopoiesis, whereas other authors have demonstrate...

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Hlavní autoři: Granick, Jennifer L., Falahee, Patrick C., Dahmubed, Delsheen, Borjesson, Dori L., Miller, Lloyd S., Simon, Scott I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2013
Témata:
Phagocytes, Granulocytes, and Myelopoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765058/
https://ncbi.nlm.nih.gov/pubmed/23869087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-466268
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