Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage

Fanconi anemia (FA) is a genetically heterogeneous, autosomal recessive disorder characterized by pediatric bone marrow failure and congenital anomalies. The effect of FA gene deficiency on hematopoietic development in utero remains poorly described as mouse models of FA do not develop hematopoietic...

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Bibliografiska uppgifter
Huvudupphovsmän: Tulpule, Asmin, Lensch, M. William, Miller, Justine D., Austin, Karyn, D'Andrea, Alan, Schlaeger, Thorsten M., Shimamura, Akiko, Daley, George Q.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2010
Ämnen:
Hematopoiesis and Stem Cells
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867260/
https://ncbi.nlm.nih.gov/pubmed/20089964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-246694
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