Pleiotropic role for MYCN in medulloblastoma

Medulloblastoma (MB) is the most common malignant brain tumor of childhood. Sonic Hedgehog (SHH) signaling drives a minority of MB, correlating with desmoplastic pathology and favorable outcome. The majority, however, arises independently of SHH and displays classic or large cell anaplastic (LCA) pa...

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Autors principals: Swartling, Fredrik J., Grimmer, Matthew R., Hackett, Christopher S., Northcott, Paul A., Fan, Qi-Wen, Goldenberg, David D., Lau, Jasmine, Masic, Selma, Nguyen, Kim, Yakovenko, Slava, Zhe, Xiao-Ning, Flynn Gilmer, Heather C., Collins, Rodney, Nagaoka, Mai, Phillips, Joanna J., Jenkins, Robert B., Tihan, Tarik, Vandenberg, Scott R., James, C. David, Tanaka, Kohichi, Taylor, Michael D., Weiss, William A., Chesler, Louis
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867210/
https://ncbi.nlm.nih.gov/pubmed/20478998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1907510
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