Pleiotropic role for MYCN in medulloblastoma

Medulloblastoma (MB) is the most common malignant brain tumor of childhood. Sonic Hedgehog (SHH) signaling drives a minority of MB, correlating with desmoplastic pathology and favorable outcome. The majority, however, arises independently of SHH and displays classic or large cell anaplastic (LCA) pa...

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Detalhes bibliográficos
Main Authors: Swartling, Fredrik J., Grimmer, Matthew R., Hackett, Christopher S., Northcott, Paul A., Fan, Qi-Wen, Goldenberg, David D., Lau, Jasmine, Masic, Selma, Nguyen, Kim, Yakovenko, Slava, Zhe, Xiao-Ning, Flynn Gilmer, Heather C., Collins, Rodney, Nagaoka, Mai, Phillips, Joanna J., Jenkins, Robert B., Tihan, Tarik, Vandenberg, Scott R., James, C. David, Tanaka, Kohichi, Taylor, Michael D., Weiss, William A., Chesler, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867210/
https://ncbi.nlm.nih.gov/pubmed/20478998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1907510
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