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Pleiotropic role for MYCN in medulloblastoma
Medulloblastoma (MB) is the most common malignant brain tumor of childhood. Sonic Hedgehog (SHH) signaling drives a minority of MB, correlating with desmoplastic pathology and favorable outcome. The majority, however, arises independently of SHH and displays classic or large cell anaplastic (LCA) pa...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867210/ https://ncbi.nlm.nih.gov/pubmed/20478998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1907510 |
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