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Paracrine Signaling Through MYCN Enhances Tumor-Vascular Interactions in Neuroblastoma
Neuroblastoma, a tumor of peripheral neural crest origin, numbers among the most common childhood cancers. Both amplification of the proto-oncogene MYCN and increased neoangiogenesis mark high-risk disease. Because angiogenesis is regulated by phosphatidylinositol 3-kinase (PI3K), we tested a clinic...
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| Hoofdauteurs: | , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402217/ https://ncbi.nlm.nih.gov/pubmed/22218692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002977 |
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