Paracrine Signaling Through MYCN Enhances Tumor-Vascular Interactions in Neuroblastoma

Neuroblastoma, a tumor of peripheral neural crest origin, numbers among the most common childhood cancers. Both amplification of the proto-oncogene MYCN and increased neoangiogenesis mark high-risk disease. Because angiogenesis is regulated by phosphatidylinositol 3-kinase (PI3K), we tested a clinic...

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Bibliografiset tiedot
Päätekijät: Chanthery, Yvan H., Gustafson, W. Clay, Itsara, Melissa, Persson, Anders, Hackett, Christopher S., Grimmer, Matt, Charron, Elise, Yakovenko, Slava, Kim, Grace, Matthay, Katherine K., Weiss, William A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402217/
https://ncbi.nlm.nih.gov/pubmed/22218692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002977
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