Chemotherapy-Induced Apoptosis in a Transgenic Model of Neuroblastoma Proceeds Through p53 Induction

Chemoresistance in neuroblastoma is a significant issue complicating treatment of this common pediatric solid tumor. MYCN-amplified neuroblastomas are infrequently mutated at p53 and are chemosensitive at diagnosis but acquire p53 mutations and chemoresistance with relapse. Paradoxically, Myc-driven...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chesler, Louis, Goldenberg, David D, Collins, Rodney, Grimmer, Matt, Kim, Grace E, Tihan, Tarik, Nguyen, Kim, Yakovenko, Slava, Matthay, Katherine K, Weiss, William A
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Neoplasia Press Inc. 2008
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570603/
https://ncbi.nlm.nih.gov/pubmed/18953436
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