Pleiotropic role for MYCN in medulloblastoma

Medulloblastoma (MB) is the most common malignant brain tumor of childhood. Sonic Hedgehog (SHH) signaling drives a minority of MB, correlating with desmoplastic pathology and favorable outcome. The majority, however, arises independently of SHH and displays classic or large cell anaplastic (LCA) pa...

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Bibliografiske detaljer
Main Authors: Swartling, Fredrik J., Grimmer, Matthew R., Hackett, Christopher S., Northcott, Paul A., Fan, Qi-Wen, Goldenberg, David D., Lau, Jasmine, Masic, Selma, Nguyen, Kim, Yakovenko, Slava, Zhe, Xiao-Ning, Flynn Gilmer, Heather C., Collins, Rodney, Nagaoka, Mai, Phillips, Joanna J., Jenkins, Robert B., Tihan, Tarik, Vandenberg, Scott R., James, C. David, Tanaka, Kohichi, Taylor, Michael D., Weiss, William A., Chesler, Louis
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2010
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867210/
https://ncbi.nlm.nih.gov/pubmed/20478998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1907510
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