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Biological Role of MYCN in Medulloblastoma: Novel Therapeutic Opportunities and Challenges Ahead
The constitutive and dysregulated expression of the transcription factor MYCN has a central role in the pathogenesis of the paediatric brain tumour medulloblastoma, with an increased expression of this oncogene correlating with a worse prognosis. Consequently, the genomic and functional alterations...
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| Publicado no: | Front Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8236857/ https://ncbi.nlm.nih.gov/pubmed/34195095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.694320 |
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