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Computational delineation of the catalytic step of a high-fidelity DNA polymerase
The Bacillus fragment, belonging to a class of high-fidelity polymerases, demonstrates high processivity (adding ∼115 bases per DNA binding event) and exceptional accuracy (1 error in 10(6) nucleotide incorporations) during DNA replication. We present analysis of structural rearrangements and energe...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867021/ https://ncbi.nlm.nih.gov/pubmed/20162624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.361 |
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