טוען...
A computational study of the force dependence of phosphoryl transfer during DNA synthesis by a high fidelity polymerase
High fidelity polymerases are efficient catalysts of phosphodiester bond formation during DNA replication/repair. We interpret molecular dynamics simulations of a polymerase bound to its substrate DNA and incoming nucleotide using a quasi-harmonic model to study the effect of external forces applied...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276685/ https://ncbi.nlm.nih.gov/pubmed/18352668 |
| תגים: |
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