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Calcium-driven DNA synthesis by a high-fidelity DNA polymerase
Divalent metal ions, usually Mg(2+), are required for both DNA synthesis and proofreading functions by DNA polymerases (DNA Pol). Although used as a non-reactive cofactor substitute for binding and crystallographic studies, Ca(2+) supports DNA polymerization by only one DNA Pol, Dpo4. Here, we explo...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716173/ https://ncbi.nlm.nih.gov/pubmed/29040737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx927 |
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