Synthesis and positron emission tomography studies of carbon-11-labeled imatinib (Gleevec)

INTRODUCTION: Imatinib mesylate (Gleevec) is a well known drug for treating chronic myeloid leukemia and gastrointestinal stromal tumors. Its active ingredient, imatinib ([4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridyl)-2-pyrimidinyl]amino]phenyl]benzamide), blocks the activity of s...

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Autores principales: Kil, Kun-Eek, Ding, Yu-Shin, Lin, Kuo-Shyan, Alexoff, David, Kim, Sung Won, Shea, Colleen, Xu, Youwen, Muench, Lisa, Fowler, Joanna S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866181/
https://ncbi.nlm.nih.gov/pubmed/17307123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2006.11.004
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