Yüklüyor......
Histone Deacetylase Inhibitor MS-275 Exhibits Poor Brain Penetration: Pharmacokinetic Studies of [(11)C]MS-275 using Positron Emission Tomography
[Image: see text] MS-275 (entinostat) is a histone deacetylase (HDAC) inhibitor currently in clinical trials for the treatment of several types of cancer. Recent reports have noted that MS-275 can cross the blood−brain barrier (BBB) and cause region-specific changes in rodent brain histone acetylati...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Chemical Society
2009
|
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908422/ https://ncbi.nlm.nih.gov/pubmed/20657706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn9000268 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|