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Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro
Alzheimer’s disease and other tauopathies are characterized by the intracellular accumulation of insoluble filaments of the microtubule-associated protein tau. The six canonical tau isoforms in the adult brain consist of an N-terminal “projection” domain followed by a proline-rich region, a microtub...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866057/ https://ncbi.nlm.nih.gov/pubmed/19919107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901304u |
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