Early N-Terminal Changes and Caspase-6 Cleavage of Tau in Alzheimer's Disease

Alzheimer's disease (AD) is a progressive amnestic dementia that involves post-translational hyperphosphorylation, enzymatic cleavage, and conformational alterations of the microtubule-associated protein tau. The truncation state of tau influences many of its pathologic characteristics, includi...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Horowitz, Peleg M., Patterson, Kristina R., Guillozet-Bongaarts, Angela L., Reynolds, Matthew R., Carroll, Christopher A., Weintraub, Susan T., Bennett, David A., Cryns, Vincent L., Berry, Robert W., Binder, Lester I.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2004
Teme:
Neurobiology of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729917/
https://ncbi.nlm.nih.gov/pubmed/15356202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1988-04.2004
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