A Possible Link Between Astrocyte Activation and Tau Nitration in Alzheimer's disease

Alzheimer's disease (AD) pathology has been characterized, in part, by the self-assembly of the tau molecule into neurofibrillary tangles (NFT). While different post-translational modifications have been identified that accelerate tau aggregation, nitration at tyrosine residues prevents or slow...

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Autori principali: Reyes, Juan F., Reynolds, Matthew R., Horowitz, Peleg M., Fu, Yifan, Guillozet-Bongaarts, Angela L., Berry, Robert, Binder, Lester I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766349/
https://ncbi.nlm.nih.gov/pubmed/18562203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.04.005
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