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Amyloidogenic sequences in native protein structures
Numerous short peptides have been shown to form β-sheet amyloid aggregates in vitro. Proteins that contain such sequences are likely to be problematic for a cell, due to their potential to aggregate into toxic structures. We investigated the structures of 30 proteins containing 45 sequences known to...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865711/ https://ncbi.nlm.nih.gov/pubmed/20027621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.314 |
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