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Hormone Binding and Co-regulator Binding to the Glucocorticoid Receptor are Allosterically Coupled
The glucocorticoid receptor initiates the cellular response to glucocorticoid steroid hormones in vertebrates. Co-regulator proteins dock to the receptor in response to hormone binding and potentiate the transcriptional activity of the receptor by modifying DNA and recruiting essential transcription...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865338/ https://ncbi.nlm.nih.gov/pubmed/20335180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.108118 |
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