Species-Specific Antagonism of Host ISGylation by the Influenza B Virus NS1 Protein

Interferon-stimulated expression and conjugation of the ubiquitin-like modifier ISG15 restricts replication of several viruses. Here, we established complete E1-activating, E2-conjugating, and E3 ligase-dependent expression systems for assaying both human and mouse ISGylation. We confirm that human...

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Detalhes bibliográficos
Principais autores: Versteeg, Gijs A., Hale, Benjamin G., van Boheemen, Sander, Wolff, Thorsten, Lenschow, Deborah J., García-Sastre, Adolfo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863827/
https://ncbi.nlm.nih.gov/pubmed/20219937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02395-09
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