Lataa...
Contribution of NS1 Effector Domain Dimerization to Influenza A Virus Replication and Virulence
Conserved tryptophan-187 facilitates homodimerization of the influenza A virus NS1 protein effector domain. We generated a mutant influenza virus strain expressing NS1-W187R to destabilize this self-interaction. NS1-W187R protein exhibited lower double-stranded RNA (dsRNA)-binding activity, showed a...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Microbiology
2012
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497675/ https://ncbi.nlm.nih.gov/pubmed/22993153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02237-12 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|