A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain

Influenza A virus NS1 protein is a multifunctional virulence factor consisting of an RNA binding domain (RBD), a short linker, an effector domain (ED), and a C-terminal ‘tail’. Although poorly understood, NS1 multimerization may autoregulate its actions. While RBD dimerization seems functionally con...

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Detalhes bibliográficos
Main Authors: Kerry, Philip S., Ayllon, Juan, Taylor, Margaret A., Hass, Claudia, Lewis, Andrew, García-Sastre, Adolfo, Randall, Richard E., Hale, Benjamin G., Russell, Rupert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065461/
https://ncbi.nlm.nih.gov/pubmed/21464929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017946
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