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Specific Mutations in the PB2 Protein of Influenza A Virus Compensate for the Lack of Efficient Interferon Antagonism of the NS1 Protein of Bat Influenza A-Like Viruses

Recently, two new influenza A-like viruses have been discovered in bats, A/little yellow-shouldered bat/Guatemala/060/2010 (HL17NL10) and A/flat-faced bat/Peru/033/2010 (HL18NL11). The hemagglutinin (HA)-like (HL) and neuraminidase (NA)-like (NL) proteins of these viruses lack hemagglutination and n...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Aydillo, Teresa, Ayllon, Juan, Pavlisin, Amzie, Martinez-Romero, Carles, Tripathi, Shashank, Mena, Ignacio, Moreira-Soto, Andrés, Vicente-Santos, Amanda, Corrales-Aguilar, Eugenia, Schwemmle, Martin, García-Sastre, Adolfo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972909/
https://ncbi.nlm.nih.gov/pubmed/29321309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02021-17
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