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Generation of the Pathogenic R5-Tropic Simian/Human Immunodeficiency Virus SHIV(AD8) by Serial Passaging in Rhesus Macaques
A new pathogenic R5-tropic simian/human immunodeficiency virus (SHIV) was generated following serial passaging in rhesus macaques. All 13 animals inoculated with SHIV(AD8) passaged lineages experienced marked depletions of CD4(+) T cells. Ten of these infected monkeys became normal progressors (NPs)...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863788/ https://ncbi.nlm.nih.gov/pubmed/20147396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02279-09 |
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