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Kinetic Parameters of Efflux of Penicillins by the Multidrug Efflux Transporter AcrAB-TolC of Escherichia coli

The multidrug efflux transporter AcrAB-TolC is known to pump out a diverse range of antibiotics, including β-lactams. However, the kinetic constants of the efflux process, needed for the quantitative understanding of resistance, were not available until those accompanying the efflux of some cephalos...

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Autori principali: Lim, Siew Ping, Nikaido, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863684/
https://ncbi.nlm.nih.gov/pubmed/20160052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01714-09
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