Correlation between In Vitro Activity of Posaconazole and In Vivo Efficacy against Rhizopus oryzae Infection in Mice

We have evaluated the in vitro activity of posaconazole (PSC) against 50 clinical strains of Rhizopus oryzae using a broth microdilution method, the Neo-Sensitabs tablet diffusion method, and minimal fungicidal concentration (MFC) determination. In general, PSC showed low MICs against this fungus, a...

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Detalhes bibliográficos
Main Authors: Rodríguez, M. Mar, Pastor, F. Javier, Sutton, Deanna A., Calvo, Enrique, Fothergill, Annette W., Salas, Valentina, Rinaldi, Michael G., Guarro, Josep
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863673/
https://ncbi.nlm.nih.gov/pubmed/20145077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01463-09
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