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Correlation between In Vitro Activity of Posaconazole and In Vivo Efficacy against Rhizopus oryzae Infection in Mice

We have evaluated the in vitro activity of posaconazole (PSC) against 50 clinical strains of Rhizopus oryzae using a broth microdilution method, the Neo-Sensitabs tablet diffusion method, and minimal fungicidal concentration (MFC) determination. In general, PSC showed low MICs against this fungus, a...

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Main Authors: Rodríguez, M. Mar, Pastor, F. Javier, Sutton, Deanna A., Calvo, Enrique, Fothergill, Annette W., Salas, Valentina, Rinaldi, Michael G., Guarro, Josep
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863673/
https://ncbi.nlm.nih.gov/pubmed/20145077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01463-09
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