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Minimal Role for the Circumsporozoite Protein in the Induction of Sterile Immunity by Vaccination with Live Rodent Malaria Sporozoites

Immunization with live Plasmodium sporozoites under chloroquine prophylaxis (Spz plus CQ) induces sterile immunity against sporozoite challenge in rodents and, more importantly, in humans. Full protection is obtained with substantially fewer parasites than with the classic immunization with radiatio...

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書誌詳細
主要な著者: Mauduit, Marjorie, Tewari, Rita, Depinay, Nadya, Kayibanda, Michèle, Lallemand, Eliette, Chavatte, Jean-Marc, Snounou, Georges, Rénia, Laurent, Grüner, Anne Charlotte
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863544/
https://ncbi.nlm.nih.gov/pubmed/20194600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01415-09
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