A Role for Immune Responses against Non-CS Components in the Cross-Species Protection Induced by Immunization with Irradiated Malaria Sporozoites

Immunization with irradiated Plasmodium sporozoites induces sterile immunity in rodents, monkeys and humans. The major surface component of the sporozoite the circumsporozoite protein (CS) long considered as the antigen predominantly responsible for this immunity, thus remains the leading candidate...

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Autors principals: Mauduit, Marjorie, Grüner, Anne Charlotte, Tewari, Rita, Depinay, Nadya, Kayibanda, Michèle, Chavatte, Jean-Marc, Franetich, Jean-François, Crisanti, Andrea, Mazier, Dominique, Snounou, Georges, Rénia, Laurent
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766644/
https://ncbi.nlm.nih.gov/pubmed/19890387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007717
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