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Intrapulmonary Administration of Leukotriene B(4) Enhances Pulmonary Host Defense against Pneumococcal Pneumonia
Leukotriene B(4) (LTB(4)) is a potent lipid mediator of inflammation formed by the 5-lipoxygenase (5-LO)-catalyzed oxidation of arachidonic acid. We have previously shown that (i) LTB(4) is generated during infection, (ii) its biosynthesis is essential for optimal antimicrobial host defense, (iii) L...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863513/ https://ncbi.nlm.nih.gov/pubmed/20231413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01323-09 |
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