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Dynamic Effects of Cofactors and DNA on the Oligomeric State of Human Mitochondrial DNA Helicase
We examined the effects of cofactors and DNA on the stability, oligomeric state and conformation of the human mitochondrial DNA helicase. We demonstrate that low salt conditions result in protein aggregation that may cause dissociation of oligomeric structure. The low salt sensitivity of the mitocho...
Tallennettuna:
| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863210/ https://ncbi.nlm.nih.gov/pubmed/20212038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.099663 |
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