ロード中...
A Rapid Oxime Linker-Based Library Approach to Identification of Bivalent Inhibitors of the Yersinia pestis Protein-Tyrosine Phosphatase, YopH
A bivalent tethered approach toward YopH inhibitor development is presented that joins aldehydes with mixtures of bis-aminooxy-containing linkers using oxime coupling. The methodology is characterized by its facility and ease of use and its ability to rapidly identify low micromolar affinity inhibit...
保存先:
| 主要な著者: | , , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863121/ https://ncbi.nlm.nih.gov/pubmed/20350805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.03.058 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|