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Chemical shift assignments for human apurinic/apyrimidinic endonuclease 1
Apurinic/apyrimidinic endonuclease 1 (APE1 or Ref-1) is the major enzyme in mammals for processing abasic sites in DNA. These cytotoxic and mutagenic lesions arise via spontaneous rupture of the base-sugar bond or the removal of damaged bases by a DNA glycosylase. APE1 cleaves the DNA backbone 5′ to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862823/ https://ncbi.nlm.nih.gov/pubmed/19888678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-009-9196-y |
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