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E3 Ligase Nedd4 Promotes Axon Branching by Downregulating PTEN

Regulated protein degradation via the ubiquitin-proteasome system (UPS) plays a central role in building synaptic connections, yet little is known about either which specific UPS components are involved or UPS targets in neurons. We report that inhibiting the UPS in developing Xenopus retinal gangli...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Drinjakovic, Jovana, Jung, Hosung, Campbell, Douglas S., Strochlic, Laure, Dwivedy, Asha, Holt, Christine E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862300/
https://ncbi.nlm.nih.gov/pubmed/20159448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.01.017
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