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MicroRNAs differentially regulated by Akt isoforms, control EMT and stem cell renewal in cancer cells
Although Akt is known to play a role in human cancer, the relative contribution of its three isoforms to oncogenesis remains to be determined. We expressed each isoform individually in an Akt1(−/−)/Akt2(−/−)/Akt3(−/−) cell line. MicroRNA profiling of growth factor-stimulated cells revealed unique mi...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862216/ https://ncbi.nlm.nih.gov/pubmed/19825827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000356 |
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