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Phosphoproteomics screen reveals Akt isoform-specific signals linking RNA processing to lung cancer
The three Akt isoforms are functionally distinct. Here we show that their phosphoproteomes also differ, suggesting that their functional differences are due to differences in target specificity. One of the top cellular functions differentially-regulated by Akt isoforms is RNA processing. IWS1, an RN...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947584/ https://ncbi.nlm.nih.gov/pubmed/24462114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.12.018 |
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