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The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY
The protein kinases Akt1, Akt2, and Akt3 possess nonredundant signaling properties, few of which have been investigated. Here, we present evidence for an Akt1-dependent pathway that controls interferon (IFN)-regulated gene expression and antiviral immunity. The target of this pathway is EMSY, an onc...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309773/ https://ncbi.nlm.nih.gov/pubmed/22315412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115029109 |
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