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An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state

Cancer stem-like cells (CSCs) are a highly tumorigenic cell type present as a minority population in developmentally diverse tumors and cell lines. Using a genetic screen in an inducible model of CSC formation in a breast cell line, we identify microRNAs (miRNAs) that inhibit CSC growth and are down...

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主要な著者: Polytarchou, Christos, Iliopoulos, Dimitrios, Struhl, Kevin
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437881/
https://ncbi.nlm.nih.gov/pubmed/22908280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212811109
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