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Hopping Enables a DNA Repair Glycosylase to Search Both Strands and Bypass a Bound Protein
Spontaneous DNA damage occurs throughout the genome, requiring that DNA repair enzymes search each nucleotide every cell cycle. This search is postulated to be more efficient if the enzyme can diffuse along the DNA, but our understanding of this process is incomplete. A key distinction between mecha...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2861864/ https://ncbi.nlm.nih.gov/pubmed/20201599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb1000185 |
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