ロード中...

Suppressor of Cytokine Signaling-2 Gene Disruption Promotes Apc(Min/+) Tumorigenesis and Activator Protein-1 Activation

Epigenetic in vitro and in vivo studies suggest that suppressor of cytokine signaling-2 (SOCS2) may normally limit tumorigenesis in the intestine; however, this theory has not been directly tested. We hypothesized that SOCS2 deficiency promotes spontaneous intestinal tumorigenesis in Apc(Min/+) mice...

詳細記述

保存先:
書誌詳細
主要な著者: Newton, Victoria A., Ramocki, Nicole M., Scull, Brooks P., Simmons, James G., McNaughton, Kirk, Lund, P. Kay
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861097/
https://ncbi.nlm.nih.gov/pubmed/20348236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090684
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!