Rapamycin Extends Maximal Lifespan in Cancer-Prone Mice

Aging is associated with obesity and cancer. Calorie restriction both slows down aging and delays cancer. Evidence has emerged that the nutrient-sensing mammalian target of rapamycin (mTOR) pathway is involved in cellular and organismal aging. Here we show that the mTOR inhibitor rapamycin prevents...

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Detalhes bibliográficos
Main Authors: Anisimov, Vladimir N., Zabezhinski, Mark A., Popovich, Irina G., Piskunova, Tatiana S., Semenchenko, Anna V., Tyndyk, Margarita L., Yurova, Maria N., Antoch, Marina P., Blagosklonny, Mikhail V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861075/
https://ncbi.nlm.nih.gov/pubmed/20363920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091050
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