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Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin
Target of Rapamycin (TOR) is involved in cellular and organismal aging. Rapamycin extends lifespan and delays cancer in mice. It is important to determine the minimum effective dose and frequency of its administration that still extends lifespan and prevents cancer. Previously we tested 1.5 mg/kg of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026081/ https://ncbi.nlm.nih.gov/pubmed/24556924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28164 |
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