Toward the design of mutation-resistant enzyme inhibitors: Further evaluation of the substrate envelope hypothesis

Lignende værker

• Evaluating the Substrate-Envelope Hypothesis: Structural Analysis of Novel HIV-1 Protease Inhibitors Designed To Be Robust against Drug Resistance
  af: Nalam, Madhavi N. L., et al.
  Udgivet: (2010)
• HIV-1 Protease Inhibitors from Inverse Design in the Substrate Envelope Exhibit Subnanomolar Binding to Drug-Resistant Variants
  af: Altman, Michael D., et al.
  Udgivet: (2008)
• New Approaches to HIV Protease Inhibitor Drug Design II: Testing the substrate envelope hypothesis to avoid drug resistance and discover robust inhibitors
  af: Nalam, Madhavi N. L., et al.
  Udgivet: (2008)
• Testing the Substrate-Envelope Hypothesis with Designed Pairs of Compounds
  af: Shen, Yang, et al.
  Udgivet: (2013)
• HIV-1 Protease and Substrate Coevolution Validates the Substrate Envelope As the Substrate Recognition Pattern
  af: Özen, Ayşegül, et al.
  Udgivet: (2012)