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Comparison of Error Rates in Single-Arm Versus Randomized Phase II Cancer Clinical Trials
PURPOSE: To improve the understanding of the appropriate design of phase II oncology clinical trials, we compared error rates in single-arm, historically controlled and randomized, concurrently controlled designs. PATIENTS AND METHODS: We simulated error rates of both designs separately from individ...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Clinical Oncology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860370/ https://ncbi.nlm.nih.gov/pubmed/20212253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.25.5489 |
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