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Selecting RNA aptamers for synthetic biology: investigating magnesium dependence and predicting binding affinity

The ability to generate RNA aptamers for synthetic biology using in vitro selection depends on the informational complexity (IC) needed to specify functional structures that bind target ligands with desired affinities in physiological concentrations of magnesium. We investigate how selection for hig...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Carothers, James M., Goler, Jonathan A., Kapoor, Yuvraaj, Lara, Lesley, Keasling, Jay D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860116/
https://ncbi.nlm.nih.gov/pubmed/20159999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq082
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