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Selecting RNA aptamers for synthetic biology: investigating magnesium dependence and predicting binding affinity
The ability to generate RNA aptamers for synthetic biology using in vitro selection depends on the informational complexity (IC) needed to specify functional structures that bind target ligands with desired affinities in physiological concentrations of magnesium. We investigate how selection for hig...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860116/ https://ncbi.nlm.nih.gov/pubmed/20159999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq082 |
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