Nalaganje...
A poke in the eye: Inhibiting HIV-1 protease through its flap-recognition pocket
A novel mechanism of inhibiting HIV-1 protease (HIVp) is presented. Using computational solvent mapping to identify complementary interactions and the Multiple Protein Structure method to incorporate protein flexibility, we generated a receptor-based pharmacophore model of the flexible flap region o...
Shranjeno v:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859825/ https://ncbi.nlm.nih.gov/pubmed/18381626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.20993 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|