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Chemical Probes That Selectively Recognize the Earliest Aβ Oligomers in Complex Mixtures

[Image: see text] Alzheimer’s disease (AD) is characterized by the self-assembly of amyloid beta (Aβ) peptides. Recent models implicate some of the earliest Aβ oligomers, such as trimers and tetramers, in disease. However, the roles of these structures remain uncertain, in part, because selective pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Reinke, Ashley A., Ung, Peter M. U., Quintero, Jerome J., Carlson, Heather A., Gestwicki, Jason E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005376/
https://ncbi.nlm.nih.gov/pubmed/21105683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja106291e
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