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Absence of Myeloid COX-2 Attenuates Acute Inflammation But Does Not Influence Development of Atherosclerosis in Apolipoprotein E Null Mice

OBJECTIVE: The role of myeloid cell cyclooxygenase-2 (COX-2) in the progression of atherosclerosis has not been clearly defined. METHODS AND RESULTS: We investigated the role of COX-2 expressed in the myeloid lineage in the development of atherosclerosis using a myeloid-specific COX-2(−/−) (COX-2(−M...

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Detalhes bibliográficos
Main Authors: Narasimha, Ajay J., Watanabe, Junji, Ishikawa, Tomo-o, Priceman, Saul J., Wu, Lily, Herschman, Harvey R., Reddy, Srinivasa T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859183/
https://ncbi.nlm.nih.gov/pubmed/19926832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.198762
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